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DSEN Abstract Exposure to valsartan products with nitrosamine impurities in the US, Canada, and Denmark A study conducted by the Canadian Network for Observational Drug Effect Studies (CNODES) Our findings suggest that many patients received valsartan products with nitrosamine…

DSEN Abstract Angiotensin receptor blocker use in the US, UK, Canada, and Denmark after the nitrosamine recalls of 2018 A study conducted by the Canadian Network for Observational Drug Effect Studies (CNODES) In Canada, an immediate steep decline in valsartan use was observed…

DSEN Abstract Is there an impact of sex (biologically male/female) differences between donors and recipients on safety and efficacy of cell therapies for immune system and autoimmune conditions? Hematopoietic stem cell transplantation (HSCT) is a promising option for persons with…

DSEN Abstract A rapid review of best practice guidance of the management of chronic pain and concurrent mental illness and/or substance use disorders High quality evidence best practice guidance is lacking for the management of chronic pain and concurrent mental illness and/or…

DSEN Abstract Effectiveness of antibiotic prophylaxis in close contacts of invasive group A streptococci infection Close contacts of patients with invasive GAS (iGAS) infection are at an increased risk of also contracting GAS We aimed to determine if antibiotic prophylaxis…

DSEN Abstract A Rapid Review of Best Practice Guidance to Reduce the Risk of Transition from Acute to Chronic Post-surgical Pain This research was funded by CIHR- Drug Safety and Effectiveness Network High-quality best practice guidance is lacking for interventions that are…

DSEN Abstract A Rapid Review of Best Practice Guidance of the Management of Chronic Pain and Concurrent Mental Illness and/or Substance Use Disorders This research was funded by CIHR- Drug Safety and Effectiveness Network High quality evidence is lacking for the best practice…

DSEN Abstract Effectiveness and safety of antiviral or antibody treatments for coronavirus This research was funded by CIHR- Drug Safety and Effectiveness Network A comprehensive literature search of both electronic databases and grey literature sources resulted in 54 studies of…

DSEN Abstract Systematic Review on the Cost-Effectiveness of Seasonal Influenza Vaccines in Older Adults We conducted a systematic review to assess the relative cost-effectiveness of various influenza vaccine options for older adults. We identified 27 eligible studies and 40…

DSEN Abstract Trivalent and quadrivalent seasonal influenza vaccine in adults aged 60 and older: a systematic review and network meta-analysis We conducted a systematic review and network meta-analysis to compare the effectiveness of influenza vaccines. Overall, our results…