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DSEN Abstract Safety and effectiveness of dose-sparing strategies for intramuscular seasonal influenza vaccine: A rapid scoping review Summary The rapid scoping review aimed to identify studies of dose-sparing strategies for administration of intramuscular seasonal influenza…

DSEN Abstract Immunogenicity and Safety of Reduced-Dose Intradermal vs Intramuscular Influenza Vaccines: A Systematic Review and Meta-analysis Summary A systematic review and meta-analysis examined the immunogenicity and safety of intradermal and intramuscular influenza vaccines.…

DSEN Abstract Effectiveness and safety of treatments for COVID-19 and other coronaviruses: A rapid scoping review This research was funded by the Drug Safety and Effectiveness Network (DSEN) and conducted by the following investigators: Andrea C. Tricco, and the MAGIC research…

DSEN Abstract Prescription patterns of ranitidine, nizatidine, famotidine, and cimetidine in Canada A study conducted by the Canadian Network for Observational Drug Effect Studies (CNODES) This large drug utilization review of histamine-2 receptor antagonists (H2RA) involved over…

DSEN Abstract Prescription patterns of ranitidine, nizatidine, famotidine, and cimetidine in Canada In 2019, some batches of ranitidine, a readily available histamine H-2 receptor antagonist that counteracts stomach acid, contained an impurity called N-nitrosodimethylamine…

DSEN Abstract A rapid review of best practice guidance to reduce the risk of transition from acute to chronic pain High-quality best practice guidance is lacking for interventions that are generalizable across patient conditions to reduce the risk of transition from acute to…

DSEN Abstract The impact of donor-recipient sex and age on the comparative efficacy and safety of human mesenchymal stromal/stem cell allogeneic treatments for autoimmune conditions: A systematic review Summary This systematic review aimed to examine how donor-recipient…

DSEN Abstract Safety of live, replicating smallpox vaccine in contraindicated populations: A systematic review Summary We conducted a systematic review to summarize the comparative harms of prophylaxis using live, replicating smallpox vaccines in contraindicated populations. Data…

DSEN Abstract Safety and effectiveness of influenza vaccine during pregnancy—a systematic review Seasonal influenza vaccination during pregnancy may be associated with reduced risk of lab-confirmed influenza and hospitalization due to lab-confirmed influenza in both mothers and…

DSEN Abstract Effectiveness and safety of antibiotic prophylaxis for persons exposed to cases of invasive group A streptococcal disease Thirty-seven studies including 26 outbreak investigations and 11 case series/reports were included in this systematic review. Limited…