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Naloxone

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How naloxone works

Naloxone only works temporarily

Naloxone is safe

Types of naloxone kits available

Where to get naloxone in your province or territory

How naloxone is helping to address Canada's opioid crisis

How naloxone works

Naloxone (pronounced na-LOX-own) is a fast-acting medication used to temporarily reverse the effects of opioid overdoses, also called an opioid poisoning.

Naloxone can begin to take effect within 2 minutes. If a response to an initial dose is not seen within 2-3 minutes, subsequent doses can safely be given. When you take an opioid, it affects certain receptors in your brain. Naloxone works by kicking opioids off the receptors in your brain and binding to those receptors instead. This reverses or blocks the effects of opioids on your body.

Naloxone only works if you have opioids in your system, such as:

fentanyl

heroin

morphine

codeine

Naloxone only works temporarily

While naloxone is only active in the body for 30 to 120 minutes, the effects of most opioids last longer. This means that the effects of naloxone are likely to wear off before the opioids are gone from the body, which causes breathing to stop again.

Naloxone may need to be used again, depending on the amount or type of opioid taken, or how the opioids were taken (for example: oral, injection).

If you suspect an overdose:

Know the

signs of an overdose

Stay and help. You can help save a life

Call 911 (or your local emergency help line)

Administer naloxone, if you have it

Know that the

Good Samaritan Drug Overdose Act

protects you from simple drug possession charges

Naloxone is safe

Naloxone is safe for all ages. It only works if you have opioids in your system. You cannot use naloxone improperly and does not create dependence. It is safe to keep a naloxone kit on hand.

Types of naloxone kits available

In Canada, 2 types of take-home kits are available:

Naloxone nasal spray

is sprayed directly into the nose, where it is absorbed.

Learn how to give naloxone spray (video)

.

Naloxone injectable

is injected into any muscle in the body, such as the arm or thigh.

Learn how to give a naloxone injection (video)

.

Where to get naloxone in your province or territory

Take-home naloxone kits are available at most pharmacies. A prescription is not needed. Ask the pharmacist.

Some provinces offer free take-home naloxone kits. Consult your province to see where these kits are available.

Alberta

British Columbia

Manitoba

New Brunswick

Check your local pharmacy or harm reduction centers:

ENSEMBLE

AIDS New Brunswick

Avenue B - Reducing Harm. Inspiring Change

Newfoundland and Labrador

Northwest Territories

Nova Scotia

Nunavut

Ontario

Prince Edward Island

Quebec

Saskatchewan

Yukon

How naloxone is helping to address Canada's overdose crisis

Naloxone kits have successfully reversed thousands of overdoses across Canada.

Naloxone is used by first-responders, including paramedics and firefighters. Take-home kits are also available at most pharmacies or local health authorities for anyone who is at risk of an overdose or who is likely to encounter one.

For more information

About opioids

Naloxone: Save a Life (fact sheet)

Substance use

Opioid overdose

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