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DSEN Abstract Predictors of Chronic Opioid Use in Non-Cancer Community-Dwelling Patients This research was funded by the Drug Safety and Effectiveness Network (DSEN) and conducted by the following investigators: Yola Moride, Cristiano Soares de Moura, Sasha Bernatsky. The…

DSEN Abstract Associations between industry incentives received by healthcare professionals and impact on drug prescribing and patient outcomes This research was funded by the Drug Safety and Effectiveness Network (DSEN) and conducted by the following investigators: Candyce…

DSEN Abstract Allergen immunotherapy for the treatment of allergic rhinitis and/or asthma: an umbrella review Summary We conducted an umbrella review to summarize the benefits and harms of subcutaneous and sublingual immunotherapy for children and adults with allergic rhinitis or…

DSEN Abstract Comparative Efficacy and Safety of Ultra-Long-, Long-, and Intermediate-Acting and Biosimilar Insulins for Type 1 Diabetes: A Systematic Review and Network Meta-Analysis We conducted a systematic review to assess the comparative effectiveness and safety of…

DSEN Abstract A content analysis of organizations and programs that implement approaches to address appropriate prescribing and use (AU) of medications This research was funded by the Drug Safety and Effectiveness Network (DSEN) and conducted by the following investigators: Alia…

DSEN Abstract CNODES Common Data Model (CDM) Pilot Project A study conducted by the Canadian Network for Observational Drug Effect Studies (CNODES) The Sentinel CDM was adapted for use in Canada at all six CNODES sites and successfully demonstrated with three pilot projects. CDM…

DSEN Abstract Direct oral anticoagulants and the risk of major bleeding in patients with non-valvular atrial fibrillation: Health Canada and European Medicines Agency collaboration A study conducted by the Canadian Network for Observational Drug Effect Studies (CNODES) This…

DSEN Abstract A Systematic Review with Network Meta-Analyses of the Comparative Safety of Bowel Cleansers for Routine Colonoscopy Evidence from randomized trials is lacking regarding the risk of ischemic colitis following the use of any bowel cleanser. Bowel cleansers containing…

DSEN Abstract Safety of Bowel Cleansers When Combined with Bisacodyl Stimulant Laxative A study conducted by the Canadian Network for Observational Drug Effect Studies (CNODES) Using bisacodyl in combination with commonly prescribed colonoscopy bowel cleansers was not associated…

DSEN Abstract Use of Domperidone and Risk of Serious Cardiac Events in Postpartum Women A study conducted by the Canadian Network for Observational Drug Effect Studies (CNODES) The incidence of cardiac death and ventricular tachyarrhythmia is very low in postpartum women.…